Friday, September 30, 2016

Men and the Fight Against Breast Cancer



Breast cancer is most heavily associated with female patients. In fact, the chances of women getting diagnosed with breast cancer in their lifetime is one in 8. However, men can also get breast cancer, although their chances of developing it are significantly lower, at one in 1,000. 

2016 has been the year of breast cancer awareness for men, as shown in an Oklahoma man who has recently been urging both men and women to check themselves for signs of breast cancer named Anthony Merka. He was diagnosed four years ago when his wife tickled him and discovered a lump, he told Fox News. Merka later had a double mastectomy to treat his disease, and since one of his daughters was found to have the BCRA mutation (which strongly increases a person’s risk of breast cancer,) she goes to the doctor every six months for regular breast cancer tests.

2,600 men will be diagnosed with breast cancer in 2016 and 440 will die from the disease. And since it is so rare for men to get breast cancer, a lot of the time male cases will go undiagnosed for some time and are more likely to be at a later, deadlier stage once discovered.

Just because men are not often diagnosed with breast cancer doesn’t mean they shouldn’t self-exam, and in cases of a family history of the disease, or those that have mutations in the BRCA gene, screening for the disease by doing careful breast exams may be useful.

2016 also sees the launch of the "Real Men Wear Pink Campaign,” which was conceived by the New York and New Jersey chapters of the American Cancer Society. The program raises awareness about breast cancer by enlisting 25 prominent community leaders in the lower Hudson Valley, including a mix of business executives, medical professionals, and politicians. For the event, participants, who have all been affected by breast cancer in some way, are asked to wear a pink article of clothing every day throughout the month of October and commit to raising $2,500 for the cause through their social media networks and community outreach.

The program kicks off fundraising for “Making Strides Against Breast Cancer Walk of Westchester” scheduled for October 16th in Purchase. “It’s a way to get men more involved with the organization,” said Lillian Jones of the American Cancer Society. “What I found is the participants are finding a way to honor the people they know. It is an opportunity to help other people that makes sense for them.”

12 million participants of ‘Making Strides Against Breast Cancer’ since 1993 have helped raise over $750 million for the disease. “We are very excited,” said Jones. “It was really amazing because it’s been really positive for the men who are finding out ways to compete against one another.”



Friday, September 23, 2016

14 Things to Do in Lake County in October

For October, I didn't even limit myself to five events to do in Lake County, because there are way more than five. There are an absolute ton of things to do in Lake County this October - from art fests to stage shows, to lots of Halloween frights. Mark your calendars!

- - - 




Select dates in September, October, and November; check site for details.

Long and Scott’s Farm

26216 County Road 448A, Mount Dora

Scott’s Maze Adventures started years ago as a simple 7-acre corn field, but has since become a fun and educational activity for the entire family. Each year the corn maze is different and has a unique theme so it is a different experience every year!






Select dates in September and October; check site for details.

The IceHouse Theatre

1100 N. Unser Street, Mount Dora

In this popular play, one actor plays twins – one a British actor, the other incredibly wealthy – where one continually attempts to get rid of the other. However, things don’t go exactly according to plan.






Saturday, October 1st – Sunday, October 2nd, 2016

Renniger’s  Antique Center

20651 U.S. Highway 441, Mount Dora

At the 5th annual Fall in the Field, there’ll be plenty of opportunity for pumpkin picking in the designer pumpkin patch, live music  to jam to, eating tons of delicious food, Fall crafts, a Kid’s Zone with face painting, and more!






Sunday, October 2nd, 2016

South Lake Moose 1615

17335 US 27, Minneola

Come out for a rib cook-off dinner, live music, and more, in order to raise funds to benefit the Bradley Summersill Foundation.






Friday, October 7th – Sunday, October 9th, 2016

Mount Dora Chamber of Commerce

341 N. Alexander Street., Mount Dora

This year marks the 42nd annual Mount Dora Bicycle Festival, and for a city that is one of America’s best festival cities, the bicycle festival is definitely one of their best. It will feature over 1,300 cyclists, and will have rides for all lengths and skill levels.






Saturday, October 8th – Sunday, October 9th, 2016

Ferran Park and Downtown Eustis, Eustis

The family friendly Lake County Folk Festival celebrates their 19th year this year, with plenty of  musicians, crafters, artists, and food vendors. There will be 9 different venues featuring over 50 groups and more than 150 musicians of different music genres including blues, Celtic, jazz, and folk.






Friday, October 14th – Sunday, October 16th, 2016

Venetian Gardens

201 E. Dixie Avenue, Leesburg

This three day outdoor festival will feature more than 100 activities and programs and host more than 25 birding, wildflower, and nature experts.






Friday, October 14th, 2016

Historic Downtown Clermont

685 W Montrose Street, Clermont

Every month downtown Clermont hosts a beer walk, and October is no different. With 20 + wines to sample and a free beer glass to keep with your ticket purchase,  there’s really no better place to be on this Friday night.







Saturday, October 15th, 2016

Waterfront Park

Palm Street, Clermont

This year is the 4th annual free outdoor music festival to benefit the Greater Clermont Cancer Foundation. There will be four stages, vendors, crafts, foods, and a Kids Zone.






Friday, October 21st – Sunday, October 23rd, 2016

16651 Schofield Road, Clermont

The annual Fall Festival at Southern Hill Farms is back, and there will be a giant pumpkin patch for all to enjoy with a photo taking area and pumpkins of all sizes. Indian Corn will also be available for purchase, and there will be live music, food trucks, Shipyard Beer, hayrides, a playground, and of course the Southern Hill Market that will be open and selling all of your favorite blueberry goodies as well as new fall themed goodies.






Saturday, October 22nd, 2016

AMVETS Post 2006

500 N Canal Street, Leesburg

A Halloween day for the kids, there will be plenty of fun Halloween activities, snacks, and candy.






Saturday, October 22nd – October 23rd, 2016

Downtown Mount Dora, Mount Dora

The Mount Dora Craft Fair that happens twice a year is one of the most popular events in Florida, attracting over 200,000 visitors and hosting over 350 of the best crafters in the country.






Saturday, October 29th, 2016

Downtown Clermont, Clermont

Sometimes you’re a runner, and you’d like to run a 5k, but you’re not a morning person AT ALL. If that sounds like you and you’re also a fan of Halloween themed things, you’ll love the Nightmare on the Clermont Trails 5K Night Run. There’ll be 10 unique scare zones to keep you on your toes as you run the length of the race, and when you finish zombies will greet you with glow in the dark medals and attempt to restrain their appetite. You won’t want to miss this one, so hurry up – participation is limited to 1,000 runners.






Saturday, October 29th, 2016

Monstrose Street

685 West Montrose Street, Clermont


Come out to the Clermont Harvest Festival for a free family Fall fest! There will be free parking, and all kinds of fun, family-oriented activities, including music and plenty of food.



Thursday, September 15, 2016

Mammography and breast cancer diagnosis improved by considering patient risk



At the Advances in Decision Analysis sponsored by the INFORMS Decision Analysis Society, a conference that took place June 16-18 at Georgetown University, a new approach to examining mammograms was presented in which a woman’s health risk profile would be taken into account, therefore reducing the number of cancer instances missed and also cutting the number of false positives.

The findings were presented by Mehmet U.S. Ayvaci of the University of Texas Dallas and discussed the role of risk profiling in the interpretation of mammograms.

In order to reduce false negatives by 3.7% and reduce false positives by 3.23, the researchers concluded that the patient’s risk profile information for breast cancer should be provided to the radiologist at the most advantageous time when examining the mammogram, together with statistical weighting based on profile risk. This would help alert women whose early cancer would have gone undiagnosed at an early stage.

Family history, reproductive history, age, and ethnicity, as well as others, are included as risk factors.

Providing risk profile information about women being screened for cancer may bias radiologists and the paper examines these questions in full. It also examines whether this bias actually helps make readings more accurate. In the past, available clinical evidence has been inconclusive on the use of profile information when interpreting mammograms. Profile information helps radiologists make better decisions and should be employed when reading mammograms, according to one position. A contradictory position says that profile information may bias the radiologists, however, it is unclear if bias causes harm at all.

Profile information and potential bias in mammography interpretation was explored by the authors and used a decision science technique called linear opinion pooling, which assigns weights to better aggregate probability estimates.

Three groups were analyzed on decision performance: 1.) A mammogram-only reading, with no profile information about the patient, 2.) an unbiased reading, in which radiologists consult the risk profile after examining the mammogram and 3.) biased or “influenced” readings, in which radiologists consult a women’s risk profile as they examine the mammogram. Then the conditions in which profile information could help improve biopsy decisions was examined.
The use of profile information with an appropriate weight could reduce the false positives and the number of missed cancers were revealed by numerical analysis using a clinical dataset from the Breast Cancer Surveillance Consortium, especially in comparison to cases where profile information had not been examined at all.

Breast cancer is the second most non-skin cancer. In 2013, approximately 232,000 breast cancer diagnoses were made and about 39,000 women died from the disease.







Wednesday, September 7, 2016

Memory Functions of the Aging Brain are Provided By Imaging Study



There may be a link between the long-term episodic memory function of the brain and dopamine D2 receptors, according to researchers in Europe who have been using PET and MRI brain imaging to investigate.

As a result of dementia and age, episodic memory functions often become degraded. The research could then help explain why some people suffer from memory impairment. Results of the study were published in the July 12, 2016 issue of the journal Proceedings of the National Academy of Sciences (PNAS).

The study was conducted at Umea University in Umea, Sweden by researchers who used Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) brain imaging for the study. Statistical analyses were then used as well as post processing – including 3D imaging, to study the mechanisms behind memory degradation that occurs during aging.

Patient's brain with dementia

181 people aged 64 and 68 were recruited for the study. The participants took part in memory and processing speed tests, coupled with measurements of the different parts of the brain using an MRI assessment. Then, a PET camera was used to examine differences in the D2 system of the brains of the individuals.

It was found that the D2 system was positively linked to episodic memory. The system was not linked to processing speed or working memory. D2 systems were also investigated by the researchers to learn how the D2 was affecting hippocampus function.

The director at the Umea Centre for Functional Brain Imaging, professor Lars Nyberg, said, “Our results link the dopamine D2 receptor to long term episodic memory, likely via hippocampus functioning. Episodic memory is often reduced with age and in people with dementia. Hence, impairment of the dopamine system are important to consider when attempting to understand the bases of impaired cognitive abilities due to aging.”



Resource: Umea University


ClermontRadiology.com