Tuesday, March 1, 2016

New Hybrid Technique of CT and MRI Reveals Lung Tumor Motion

Combining both magnetic resonance imaging (MRI), and computed tomography (CT) reveals tumor motion and lung motion in general, a new study shows.

Researchers from the Agency for Science, Technology, and Research (A*STAR, Singapore) have discovered a way to produce high quality images of the lungs during the breathing movement. Usually tumors in the lungs are in constant motion, due to the patients breathing; so treating them with high energy X-Rays can be quite complex. However, with this new hybrid method, it will significantly aid physicians when they target tumors in lungs during radiotherapy.

The scientists at A*STAR have combined the two techniques of CT (which provides high resolution snapshots, but is not able to track continuous motion and produces radiation safety concerns,) and 4D-MRI (which does not yield any harmful radiation and does allow for continuous tracking of lung motion but produces blurred images,) to take advantage the best of both worlds – high resolution images that accurately track lung movement during breathing.



Mathematically combining the image from the computed tomography scanner with the four dimensional images obtained by the MRI, resulted in a high resolution that showed lung tumor movement over several breathing cycles. 

Testing out their new technique on six cancer patients, it proved quite successful – the average error was less than two millimeters. The first information released on the new hybrid technique was published in the August 2015 Medical Physics.


Depending on how well the technique goes with obtaining the backing from medical equipment companies and meeting the mandatory requirements, the researchers may develop the technique for use on other organs, such as the liver, and combine it with different imaging methods to produce more comprehensive data sets.


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